A drug that delays the aging process has attracted interest from NASA
Australian scientists have identified a mechanism that ry enables the com rkom repair of damaged DNA. The discovery may help c in developing an effective op Delaying the aging process. The matter has attracted the interest of NASA, which ra would like to administer such a preparation to future Martian pilgrims.
Our com rki have an innate ability to repair DNA damage. However, this ability decreases with age. Scientists do not yet fully understand why this happens. However, the mechanism plays a key role when it comes to the lifespan of com rek.
While studying the natural process of In DNA repair, scientists at the University of New South Wales in Sydney (UNSW) have looked at the present in com rkach metabolic product NAD+. The oxidized form of nicotinamide adenine dinucleotide (NAD+) plays an important role in cellular respiration processes rkowe and is present in every com rce of our body. However, it has now been confirmed that it also plays a key role in DNA repair processes.
Syndrome ł has identified a critical step in the molecular process that ry enables the com rkom repairing damaged DNA. Studies conducted on mice have shown that it is possible to improve this process. Thus, it is possible to op Foreshortening, and perhaps even the reverse price of the process in aging.
In the experiments, the Australian researchers gave mice the NAD+ precursor of the so-called “NAD+”. NMN. The results of the experiment confirmed that the com cells undergo rejuvenation.
– Com The wounds of the old mice were irretrievable The preparation would accelerate the repair of DNA damage rek of young rodents and after only one week of treatment – Professor David Sinclair of UNSW and Harvard Medical School in Boston said. – We are very close to developing a safe and effective anti-aging drug, which ry in the event of a successful test in humans, could hit the market within three to five years – added the scientist.
Interest from NASA
The findings are so promising that they have attracted the attention of NASA, kt ra is keenly interested in such a preparation in a future mission to Mars. The US Space Agency is looking for a way to protect astronauts The preparation would accelerate the repair of damaged DNA live on the Red Planet.
Even during kr astronauts experience the negative effects of the caused by space radiation. It m.in. Muscle weakness, memory loss and other symptoms of. A preparation that accelerates the repair of damaged DNA m head to effectively counteract the effects of prolonged exposure to space. And yet, a mission to Mars will take at least a few years.
But the preparation would also have wide applications on Earth. We are all exposed to increased radiation if only during long flights in the plane of. It is estimated that during a flight from London to Melbourne we receive a dose that ra is por n comparable to that obtained during a chest X-ray. Drug m ould also support cancer therapies.
A pair of researchers with UNSW have been conducting research on NMN for the past four years. Tests involving humans are expected to begin within p ł year.